The U.S. State Department is offering a combined $10 million for information leading to the arrest or conviction of René Arzate-García, known as “La Rana,” and his brother Alfonso Arzate-García, known as “Aquiles,” two alleged senior figures in the Sinaloa Cartel. Authorities say the brothers have controlled the so-called Tijuana Plaza for approximately 15 years, managing a major trafficking corridor that funnels fentanyl, methamphetamine, cocaine and marijuana toward the San Diego border region.

According to the Drug Enforcement Administration, the Tijuana Plaza serves as one of the most significant drug smuggling routes into the United States. Federal prosecutors in the Southern District of California first brought drug trafficking charges against the brothers in 2014. Both men have remained fugitives.

On Thursday, the Justice Department unsealed a superseding indictment against René Arzate-García that adds charges of narcoterrorism, operating a continuing criminal enterprise, providing material support to a foreign terrorist organization, international drug trafficking conspiracy and money laundering. The expanded charges follow the Trump administration’s designation of the Sinaloa Cartel as a Foreign Terrorist Organization and a Specially Designated Global Terrorist entity last year. The Treasury Department had previously sanctioned the brothers in 2023 under an executive order targeting the global narcotics trade.

The reward announcement comes as U.S. authorities updated high-profile cartel listings following the reported death of Nemesio Oseguera Cervantes, longtime head of the rival Jalisco New Generation Cartel. Mexican security forces killed Oseguera Cervantes during an operation in Jalisco that received logistical and intelligence support from the Trump administration. The United States had previously offered up to $15 million for information leading to his capture.

In the aftermath of that operation, cartel gunmen launched coordinated retaliatory attacks across much of Mexico, with violence reaching Tijuana, where factions of the Sinaloa Cartel and CJNG remain locked in an ongoing power struggle. U.S. officials say dismantling leadership structures tied to cross-border trafficking remains a priority amid the continued flow of fentanyl into American communities.