A semitrailer carrying as many as 130 cattle plunged off a highway overpass in downtown Kansas City, Missouri, early Sunday, overturning onto a passenger car and sending surviving animals running through nearby streets.

The crash occurred shortly before 3 a.m. where the westbound Interstate 70 curve passes over southbound Interstate 35. Kansas City police said between 45 and 60 cattle were killed in the wreck, while dozens of others escaped and prompted an extensive search that continued into the afternoon.

Both the truck driver and the driver of the car struck by the trailer suffered minor injuries and were treated at local hospitals, authorities said.

The loose cattle created additional hazards around the city, with some animals wandering several miles from the crash site. Police received calls from members of the public reporting escaped cattle, and the incident led to additional crashes as the animals moved through the area.

Kansas City Fire Battalion Chief Michael Hopkins said authorities initially deployed drones to locate the animals. Workers on horseback later joined the operation through a private company working with the trucking company to round up the surviving cattle.

“It was a pretty nasty accident,” Hopkins said, describing the difficult recovery effort. Retrieving the animals that died in the crash proved particularly challenging, he added.

By Sunday, police Sgt. Phil DiMartino said authorities believed all the cattle had been accounted for, bringing the search to a close after hours of tracking and recovery work.

The crash also prompted road closures and traffic disruptions on a day when the Kansas City Chiefs were scheduled to host the Los Angeles Chargers. Authorities did not anticipate major disruptions to game-day traffic, citing the widespread publicity surrounding the accident.