At least 15 people were killed when a missile strike hit a factory in the central Iranian city of Isfahan on Saturday, Iran's semi-official Fars news agency reported. The facility, which manufactures heaters and refrigerators, was operational with workers inside at the time of the attack.

Fars attributed the strike to the "American-Zionist enemy," referring to the United States and Israel. Neither the U.S. nor Israeli militaries issued immediate statements on the incident. The attack occurred during working hours on Saturday, a standard workday in Iran.

The strike comes amid the ongoing 2026 Iran war, which began on February 28 with joint U.S.-Israeli airstrikes targeting Iranian military sites, air defenses, and missile launchers across the country. Those initial operations, dubbed Operation Epic Fury by the U.S. and Operation Roaring Lion by Israel, also resulted in the death of Supreme Leader Ali Khamenei and several top officials. Iran responded with waves of ballistic missiles and drones under Operation True Promise IV, striking Israel, U.S. bases, and allied Gulf states.

Since then, U.S. and Israeli forces have conducted repeated strikes on Iranian nuclear facilities, missile production sites, naval assets, and regime infrastructure. Earlier actions damaged sites in Isfahan linked to nuclear activities and caused harm to UNESCO World Heritage locations in the city, including Naqsh-e Jahan Square and several historic mosques. On Saturday, the U.S. carried out a major bombing raid on Iran's Kharg Island oil export hub, destroying military targets while sparing energy infrastructure, President Donald Trump announced.

Iranian authorities claim civilian casualties from the broader campaign exceed 1,400 killed and 18,000 wounded, though independent verification remains limited. Human rights groups have cited higher figures for total deaths in Iran, potentially reaching 4,900. U.S. and Israeli officials report thousands of Iranian military personnel killed.

The conflict has led Iran to close the Strait of Hormuz, disrupting global oil shipments and driving prices up more than 40 percent. Iran has launched over 1,200 ballistic missiles and 2,000 drones since the war started, but its stockpiles have dwindled significantly. Hezbollah has intensified attacks on Israel from Lebanon, prompting Israeli ground operations there.

Mojtaba Khamenei, son of the late supreme leader, assumed leadership on March 8. Ceasefire efforts have faltered, with Trump rejecting proposals for talks as recently as Saturday.

No further details on the Isfahan factory strike, such as the number of wounded or extent of damage, were immediately available from Iranian sources. The incident marks another escalation in a war that has drawn in regional actors and raised fears of wider instability.