An Iranian ballistic missile struck a residential building in Beit Shemesh, a city west of Jerusalem, killing eight Israelis and injuring nearly 30 others on Sunday afternoon. Israel's Magen David Adom emergency service confirmed the death toll rose to eight, with four people critically wounded and others hospitalized. Search and rescue operations continued at the site, where several people remained missing.

The strike marked the deadliest incident in Israel since Iran launched retaliatory missile barrages following joint U.S.-Israeli attacks on Saturday that killed Supreme Leader Ayatollah Ali Khamenei and several top military commanders. A separate Iranian missile hit the Tel Aviv area earlier, killing one woman and injuring more than 20 people. Iranian forces fired around 150 ballistic missiles and dozens of drones at Israel, with most intercepted by defenses but several causing impacts.

The U.S. and Israel began strikes on Iran Saturday morning, targeting leadership, ballistic missile sites, and nuclear facilities. Khamenei, 86, died in an attack on his Tehran compound, along with Islamic Revolutionary Guard Corps commander Gen. Mohammad Pakpour, Defense Minister Gen. Aziz Nasirzadeh, armed forces chief Sayyid Abdolrahim Mousavi, and adviser Adm. Ali Shamkhani. Iranian reports indicated over 200 deaths, including 148 students at a girls' school in Minab.

Iran responded by targeting U.S. bases and allies across the Gulf, including Bahrain, Kuwait, Qatar, the United Arab Emirates, and Jordan. In Kuwait, one person died and 32 were injured; Bahrain reported injuries at a hotel; the UAE saw one death and several injuries from debris. Shipping through the Strait of Hormuz halted, disrupting one-fifth of global oil supplies, while major airports closed and airlines suspended flights.

Israel launched fresh strikes on Tehran Sunday, hitting the city center as Iran formed an interim leadership council with President Masoud Pezeshkian, judiciary head Gholam-Hossein Mohseni-Eje’i, and cleric Ayatollah Alireza Arafi. Israeli Defense Minister Israel Katz called Khamenei's death a turning point, stating operations would continue to enable regime change. President Donald Trump announced the strikes on social media, while Iranian officials vowed further powerful responses.

OPEC+ planned to boost oil production by 206,000 barrels per day amid rising prices. Airspace closures persisted across the region, with no immediate end to the exchanges.