The Centers for Disease Control and Prevention declared on Friday that a multistate cyclosporiasis outbreak linked to contaminated iceberg lettuce has ended.

The outbreak, tied to processed iceberg lettuce from Taylor Farms de Mexico, sickened 12,883 people across 21 states. It resulted in 570 hospitalizations and two deaths. This marked the largest recorded cyclosporiasis outbreak in U.S. history.

Cyclosporiasis is an intestinal illness caused by the Cyclospora parasite, typically spread through contaminated food or water. Symptoms include prolonged diarrhea, stomach cramps, nausea, and fatigue.

CDC officials cited a significant decline in recent infections and the removal of all implicated products from stores and restaurants as reasons for ending the alert. The best-by dates for the recalled lettuce have passed, and the contaminated items are no longer available.

Taylor Farms de Mexico issued a recall of all iceberg lettuce sourced from central Mexico on July 17, 2026. Illnesses began as early as June 14 and continued through August 17.

The outbreak drove much of the national increase in cases this season. CDC data show 19,595 laboratory-confirmed cyclosporiasis cases reported in the United States since May 1, compared to 1,180 during the same period in 2025. Michigan reported the highest number of cases, with over 14,000 infections and both deaths linked to the parasite. Ohio and Missouri also saw thousands of infections.

The Food and Drug Administration continues to investigate the source of the contamination at Taylor Farms facilities in Mexico. The agency has completed inspections and sample collection at processing plants and growing fields.

The outbreak led to a notable reduction in sales at restaurants and grocery stores selling fresh lettuce. Federal officials noted that the recall and subsequent actions removed the risk from this specific source.