The Pennsylvania Department of Health confirmed Tuesday that two unvaccinated residents of Lancaster County died from measles complications.

These mark the first measles-related deaths in the state in 35 years. Officials did not release further identifying details about the individuals to protect family privacy.

"My deepest sympathies are with the loved ones who are facing this unimaginable loss," said Secretary of Health Dr. Debra Bogen. "Because measles was largely eliminated in the Commonwealth for more than three decades, people are not familiar with this disease and don’t fully understand the potential severity of the illness."

Bogen emphasized that the MMR vaccine remains safe and offers the best protection available. The department noted that the vaccine, given in two doses, provides 97 percent lifetime protection.

Pennsylvania has recorded 393 confirmed measles cases across 29 counties so far in 2026. Lancaster County accounts for a significant portion of those cases.

Measles spreads easily through respiratory droplets and can lead to serious complications such as pneumonia and brain swelling. Nearly 20 percent of infected individuals require hospitalization, and deaths occur in roughly one to three cases per 1,000, according to state health data.

The announcement comes amid a broader national resurgence of the disease, with U.S. cases exceeding totals from recent decades.